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Oral GLP-1 formulations offer convenience for needle-averse patients but require specific timing with meals and water intake to maximize absorption

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Systematic rotation between injection sites prevents tissue changes (lipohypertrophy) that impair medication absorption and glucose control

It also has other effects, it is neuroprotective, increases bone formation, decreases stomach acid secretion, increases insulin release, stimulates fatty acid synthesis, and seems to promote the weight loss effect of GLP-1R activation